麻豆淫院

The efficient use of cellulose鈥攖he primary plant scaffold and a major natural building block鈥攃ould address many issues associated with petroleum-based polymers across various industries. In the search for more sustainable uses of cellulose, Lithuanian scientists have developed a production method for a nanofibrous cellulose matrix, which has the potential to replace non-renewable industrial even in biomedical applications.

Textile, clothing, toys, and sports equipment made from synthetic petroleum-based materials have a significant negative impact on the environment through their entire life cycle, from production to waste management.

Scientists argue that it is necessary to replace petroleum-based materials with environmentally friendly materials and to demonstrate to consumers that products that have been in use for many years can be replaced while retaining their effectiveness. According to Ingrida Pauliukaityt臈, a Ph.D. student at Kaunas University of Technology (KTU) and one of the creators of the new environmentally friendly cellulose nanofiber, the invention is a step towards a more sustainable industry.

A paper describing this work is in the Journal of Biomedical Materials Research Part A.

A unique production method

Cellulose is the Earth's most abundant and widespread natural polysaccharide, commonly found in plant cell walls, algae or synthesized by certain bacteria.

"I chose cellulose as a research object because of its natural origin and favorable properties: its biocompatibility and degradability, variety of chemical strains, and wide range of applications," says the inventor.

The invention was developed using the wet-type electrospinning method, whereby cellulose is dissolved in special solvents鈥攊onic liquids鈥攁nd the solution is then converted into fibers.

"This is a method that allows the creation of cellulose matrices with a unique gel-like structure, similar to cellulose fibers naturally synthesized by bacteria," says the Ph.D. student at the KTU Faculty of Chemical Technology (CTF).

This method of creating cellulose has an advantage in the market due to its environmental friendliness. In particular, the dissolution method used is more environmentally friendly due to the use of "green solvents."

Also, the raw material for this production process can be either raw cellulose or cellulose waste. Depending on the purity of the material, the resulting fiber can be used for different products. The recycled cellulose can be used to produce new polymer composite products such as toys, sports equipment, household items. If the raw material is pure plant cellulose, biomedical applications have great potential, where this type of nanofibrous structure has unique biocompatibility properties.

A significant boost for cancer research

"Our invention鈥攁 nanofibrous cellulose matrix鈥攊s like a scaffold, a structural support that helps cells to divide and grow," explains Pauliukaityt臈.

The biocompatibility Pauliukaityt臈 mentions is very important in tissue engineering to prevent the living organism's immune response to a material used for cell reproduction other than the one naturally synthesized by the organism.

"In addition, cellulose has very favorable mechanical properties, so that the fibers developed are strong and can withstand the high stresses that arise when cells proliferate. Since cellulose absorbs water, the use of cellulose fibers in wound healing can control the amount of moisture that occurs during the healing process," says Pauliukaityt臈.

So far, the applicability of cellulose in tissue engineering has been tested for the reconstruction of cartilage, bone and vascular structures. However, given the biocompatibility, structural and moisture retention properties of cellulose, this polymer has great potential for use in regenerative medicine, which aims to stimulate the body's natural recovery mechanisms and restore lost biological functions, and for organ growth.

In addition, the cellulose nanofibers developed are not only biocompatible and environmentally friendly, but also have the potential to form three-dimensional (3D) cell models that better reflect cell behavior in the natural environment.

"This is a significant advantage, especially in tissue engineering and cancer research, as 3D cultures allow for more precise experiments and a better understanding of cell growth and interactions," says Pauliukaityt臈.